Haemorrhagic Diathesis Due to Deficiency of Factor VII

Haemorrhagic diathesis due to deficiency of factor VII.

Of recent years it has become apparent that Quick's one-stage prothrombin time, although a most useful routine laboratory test, does not specifically measure plasma prothrombin. Quick himself (1947) recognized that deficiency of his labile factor (Factor V) caused lengthening of the prothrombin time, and Owren (1947) reported the first case of congenital deficiency of Factor V causing a haemorr...

Relevant bleeding diathesis due to acquired factor XIII deficiency.

BACKGROUND Acquired factor XIII (FXIII) deficiency is associated with reduced clot firmness and increased bleeding in patients undergoing major surgery. In contrast, only limited information is available on the haemostatic relevance of acquired FXIII deficiency in non-surgical patients. CASE REPORT An 81-year-old patient, who had experienced acute type-A dissection of the aorta eight years ea...

Jaundice and factor VII deficiency in newborn

Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...

Haemorrhagic diathesis in children associated with vitamin K deficiency.

A haemorrhagic diathesis is described in infants; this is preceded and accompanied by constitutional symptoms such as fever, diarrhoea, vomiting, anorexia, and pallor. These children had a severe coagulation abnormality, due to deficiency of vitamin-K-dependent coagulation factors, and it was corrected by administration of vitamin K. No conclusion could be drawn as to the aetiology of this cond...

Inherited factor VII deficiency